TY - JOUR
T1 - Imaging of iris lesions with high-speed optical coherence tomography
AU - Bakri, Sophie J.
AU - Singh, Arun D.
AU - Lowder, Careen Y.
AU - Chalita, Maria Regina
AU - Li, Yan
AU - Izatt, Joseph A.
AU - Rollins, Andrew M.
AU - Huang, David
PY - 2007
Y1 - 2007
N2 - ■ BACKGROUND AND OBJECTIVES: To image and measure iris tumors with optical coherence tomography (OCT). ■ PATIENTS AND METHODS: High-speed (2,000-4,000 axial-scan/sec and 4-16 frames/sec) 1.3-micron wavelength anterior segment OCT prototypes were used to image 6 eyes of 6 patients with a variety of iris lesions, including focal iris nevus, diffuse iris nevus, amelanotic iris nevus, iris melanocytosis, and iris melanoma. OCT images were compared with slit-lamp photography and ultrasound biomicroscopy. ■ RESULTS: OCT at 1.3-micron wavelength could penetrate the full thickness of the iris lesions and allow three-dimensional measurement of lesion size. Internal reflectivity is correlated with pigmentation. OCT is a convenient non-contact method that provides imaging of the clinically important angle structures (scleral spur and angle recess). ■ CONCLUSIONS: OCT is a new imaging modality that complements slit-lamp photography and ultrasound biomicroscopy for serial evaluation of iris lesions.
AB - ■ BACKGROUND AND OBJECTIVES: To image and measure iris tumors with optical coherence tomography (OCT). ■ PATIENTS AND METHODS: High-speed (2,000-4,000 axial-scan/sec and 4-16 frames/sec) 1.3-micron wavelength anterior segment OCT prototypes were used to image 6 eyes of 6 patients with a variety of iris lesions, including focal iris nevus, diffuse iris nevus, amelanotic iris nevus, iris melanocytosis, and iris melanoma. OCT images were compared with slit-lamp photography and ultrasound biomicroscopy. ■ RESULTS: OCT at 1.3-micron wavelength could penetrate the full thickness of the iris lesions and allow three-dimensional measurement of lesion size. Internal reflectivity is correlated with pigmentation. OCT is a convenient non-contact method that provides imaging of the clinically important angle structures (scleral spur and angle recess). ■ CONCLUSIONS: OCT is a new imaging modality that complements slit-lamp photography and ultrasound biomicroscopy for serial evaluation of iris lesions.
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U2 - 10.3928/15428877-20070101-04
DO - 10.3928/15428877-20070101-04
M3 - Article
C2 - 17278533
AN - SCOPUS:33846799122
SN - 2325-8160
VL - 38
SP - 27
EP - 34
JO - Ophthalmic Surgery and Lasers
JF - Ophthalmic Surgery and Lasers
IS - 1
ER -