Abstract
The precise histologic localization of GLUT3, a glucose transporter thought to be restricted to neurons, is unknown. Using a high-affinity, specific antiserum against rodent GLUT3 for immunocytochemistry, light microscopic staining concentrates heterogeneously in the neuropil in a region- and lamina-specific manner; intense staining characterizes areas with high rates of glucose utilization such as inferior colliculus and pyriform cortex. Neuropil localization with little perikaryal staining suggests that GLUT3 may provide the energy needed locally for synaptic transmission.
Original language | English (US) |
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Pages (from-to) | 292-297 |
Number of pages | 6 |
Journal | Brain research |
Volume | 659 |
Issue number | 1-2 |
DOIs | |
State | Published - Oct 3 1994 |
Keywords
- Brain metabolism
- Energy metabolism
- Glucose transporter
- Immunocytochemistry
- Synapse
ASJC Scopus subject areas
- General Neuroscience
- Molecular Biology
- Clinical Neurology
- Developmental Biology