Implications of the frequent hemodialysis network-daily trial

Kalani L. Raphael, Alfred K. Cheung

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Despite many years of experience with hemodialysis, the outcomes of maintenance dialysis patients remain poor. The Frequent Hemodialysis Network-Daily (FHN-Daily) Trial found that six times per week in-center short hemodialysis decreased left ventricular mass and improved self-reported physical functioning over a 1-year intervention period compared with conventional thrice-weekly dialysis. Despite the promising results, caution is needed in the projection of these intermediate outcomes to hard clinical endpoints, such as cardiovascular events and death. Published 2011. This article is a US Government work and is in the public domain in the USA.

Original languageEnglish (US)
Pages (from-to)621-628
Number of pages8
JournalSeminars in Dialysis
Issue number6
StatePublished - Nov 2011
Externally publishedYes

ASJC Scopus subject areas

  • Nephrology


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