TY - JOUR
T1 - Indications and applications of arterial stents for stroke prevention in atherosclerotic intracranial stenosis
AU - Fields, Jeremy D.
AU - Liu, Kenneth C.
AU - Barnwell, Stanley L.
AU - Clark, Wayne M.
AU - Lutsep, Helmi L.
N1 - Funding Information:
As opposed to the Neurolink Stent System, the Wingspan system (Boston Scientific, Natick, MA) is a self-expanding stent. The primary experience with Wingspan has been reported from three sources: an initial study that led the US Food and Drug Administration to grant an HDE for the device, a US National Institutes of Health (NIH)—sponsored multicenter registry, and a company-sponsored registry.
PY - 2010/1
Y1 - 2010/1
N2 - Intracranial stenosis accounts for 8-10% of all ischemic strokes in North America, a frequency slightly less than that of extracranial carotid stenosis. Among patients presenting with transient ischemic attack or stroke due to intracranial stenosis, the risk of recurrent stroke in the first year after initial symptoms is about 14%. Those with high-risk features (recent stroke and severe stenosis) have up to a 23% rate of recurrent stroke in the year after their initial event. Angioplasty with stenting has emerged as a potential treatment strategy, particularly in high-risk patients, although evidence is currently limited to uncontrolled prospective trials and retrospective case series. In this article, we critically review the clinical results supporting the use of stenting and highlight some key considerations in the application of this technology, including patient selection, procedural management, technical issues, and risk factors for complications and in-stent restenosis.
AB - Intracranial stenosis accounts for 8-10% of all ischemic strokes in North America, a frequency slightly less than that of extracranial carotid stenosis. Among patients presenting with transient ischemic attack or stroke due to intracranial stenosis, the risk of recurrent stroke in the first year after initial symptoms is about 14%. Those with high-risk features (recent stroke and severe stenosis) have up to a 23% rate of recurrent stroke in the year after their initial event. Angioplasty with stenting has emerged as a potential treatment strategy, particularly in high-risk patients, although evidence is currently limited to uncontrolled prospective trials and retrospective case series. In this article, we critically review the clinical results supporting the use of stenting and highlight some key considerations in the application of this technology, including patient selection, procedural management, technical issues, and risk factors for complications and in-stent restenosis.
KW - Intracranial angioplasty
KW - Intracranial atherosclerotic disease
KW - Intracranial stenosis
KW - Intracranial stent
KW - Stroke
KW - Stroke prevention
UR - http://www.scopus.com/inward/record.url?scp=77249168608&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77249168608&partnerID=8YFLogxK
U2 - 10.1007/s11886-009-0070-4
DO - 10.1007/s11886-009-0070-4
M3 - Review article
C2 - 20425180
AN - SCOPUS:77249168608
SN - 1523-3782
VL - 12
SP - 20
EP - 28
JO - Current cardiology reports
JF - Current cardiology reports
IS - 1
ER -