Infarct-related coronary artery patency and medication use prior to ST-segment elevation myocardial infarction

Christina R. Robinson; Justin L. Martin; Lily Zhang; Russell M. Canham; Shuaib M. Abdullah; Joaquin E. Cigarroa; L. David Hillis; Sabina A. Murphy; Darren K. McGuire; James A. De Lemos; Ellen C. Keeley

doi:10.1016/j.amjcard.2005.07.103

Infarct-related coronary artery patency and medication use prior to ST-segment elevation myocardial infarction

Christina R. Robinson, Justin L. Martin, Lily Zhang, Russell M. Canham, Shuaib M. Abdullah, Joaquin E. Cigarroa, L. David Hillis, Sabina A. Murphy, Darren K. McGuire, James A. De Lemos, Ellen C. Keeley

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

In patients who have ST-segment elevation myocardial infarction (STEMI), a patent infarct-related artery on the initial angiogram is associated with improved clinical outcomes, including decreased mortality. The present study assessed the influence of administering aspirin, β blockers, statins, and angiotensin-converting enzyme inhibitors before STEMI on infarct-related artery patency. Our data demonstrate that patients who have STEMI and receive these medications on an outpatient basis before the event have a higher likelihood of having a patent infarct-related artery compared with patients who do not receive these medications. Further, our data demonstrate a graded association according to the number of such medications being administered: the likelihood of a patent infarct-related artery increased to >50% as the number of these medications increased.

Original language	English (US)
Pages (from-to)	7-9
Number of pages	3
Journal	American Journal of Cardiology
Volume	97
Issue number	1
DOIs	https://doi.org/10.1016/j.amjcard.2005.07.103
State	Published - Jan 1 2006
Externally published	Yes

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/j.amjcard.2005.07.103

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Robinson, C. R., Martin, J. L., Zhang, L., Canham, R. M., Abdullah, S. M., Cigarroa, J. E., Hillis, L. D., Murphy, S. A., McGuire, D. K., De Lemos, J. A., & Keeley, E. C. (2006). Infarct-related coronary artery patency and medication use prior to ST-segment elevation myocardial infarction. American Journal of Cardiology, 97(1), 7-9. https://doi.org/10.1016/j.amjcard.2005.07.103

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title = "Infarct-related coronary artery patency and medication use prior to ST-segment elevation myocardial infarction",

abstract = "In patients who have ST-segment elevation myocardial infarction (STEMI), a patent infarct-related artery on the initial angiogram is associated with improved clinical outcomes, including decreased mortality. The present study assessed the influence of administering aspirin, β blockers, statins, and angiotensin-converting enzyme inhibitors before STEMI on infarct-related artery patency. Our data demonstrate that patients who have STEMI and receive these medications on an outpatient basis before the event have a higher likelihood of having a patent infarct-related artery compared with patients who do not receive these medications. Further, our data demonstrate a graded association according to the number of such medications being administered: the likelihood of a patent infarct-related artery increased to >50% as the number of these medications increased.",

author = "Robinson, {Christina R.} and Martin, {Justin L.} and Lily Zhang and Canham, {Russell M.} and Abdullah, {Shuaib M.} and Cigarroa, {Joaquin E.} and Hillis, {L. David} and Murphy, {Sabina A.} and McGuire, {Darren K.} and {De Lemos}, {James A.} and Keeley, {Ellen C.}",

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doi = "10.1016/j.amjcard.2005.07.103",

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T1 - Infarct-related coronary artery patency and medication use prior to ST-segment elevation myocardial infarction

AU - Robinson, Christina R.

AU - Martin, Justin L.

AU - Zhang, Lily

AU - Canham, Russell M.

AU - Abdullah, Shuaib M.

AU - Cigarroa, Joaquin E.

AU - Hillis, L. David

AU - Murphy, Sabina A.

AU - McGuire, Darren K.

AU - De Lemos, James A.

AU - Keeley, Ellen C.

PY - 2006/1/1

Y1 - 2006/1/1

N2 - In patients who have ST-segment elevation myocardial infarction (STEMI), a patent infarct-related artery on the initial angiogram is associated with improved clinical outcomes, including decreased mortality. The present study assessed the influence of administering aspirin, β blockers, statins, and angiotensin-converting enzyme inhibitors before STEMI on infarct-related artery patency. Our data demonstrate that patients who have STEMI and receive these medications on an outpatient basis before the event have a higher likelihood of having a patent infarct-related artery compared with patients who do not receive these medications. Further, our data demonstrate a graded association according to the number of such medications being administered: the likelihood of a patent infarct-related artery increased to >50% as the number of these medications increased.

AB - In patients who have ST-segment elevation myocardial infarction (STEMI), a patent infarct-related artery on the initial angiogram is associated with improved clinical outcomes, including decreased mortality. The present study assessed the influence of administering aspirin, β blockers, statins, and angiotensin-converting enzyme inhibitors before STEMI on infarct-related artery patency. Our data demonstrate that patients who have STEMI and receive these medications on an outpatient basis before the event have a higher likelihood of having a patent infarct-related artery compared with patients who do not receive these medications. Further, our data demonstrate a graded association according to the number of such medications being administered: the likelihood of a patent infarct-related artery increased to >50% as the number of these medications increased.

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Infarct-related coronary artery patency and medication use prior to ST-segment elevation myocardial infarction

Abstract

ASJC Scopus subject areas

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