Influence of age and body weight on spine and femur bone mineral density in U.S. white men

Richard B. Mazess, Howard S. Barden, Paul J. Drinka, Steven F. Bauwens, Eric S. Orwoll, Norman H. Bell

Research output: Contribution to journalArticlepeer-review

141 Scopus citations


Bone mineral density (BMD) was measured in normal white males using 153 Gd dual‐photon absorptiometry. Measurements were made on the lumbar spine (n = 315) and on the proximal femur (n = 282) utilizing three regions of interest. There was a small but significant age‐related decrease in spinal BMD (r = ‐0.11; ‐0.001 g/cm2 per year) and trochanteric BMD (r = 0.27; ‐0.002 g/cm2 per year). The BMD of the other femoral sites decreased more rapidly; the femoral neck (r = ‐0.58; ‐0.005 g/cm2 per year) and Ward's triangle (r = ‐0.69; ‐0.007 g/cm2 per year) declined by about 21 and 34%, respectively, from age 20 to age 70. These femoral BMD decreases were three to four times greater than those usually seen in the peripheral skeleton in males but less than the decreases of 25‐30 and 40% in the femoral neck and Ward's triangle of white females. This pattern of aging bone loss may partially explain the paucity of spine fractures and the lower incidence of hip fractures in males versus females.

Original languageEnglish (US)
Pages (from-to)645-652
Number of pages8
JournalJournal of Bone and Mineral Research
Issue number6
StatePublished - Jun 1990

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Orthopedics and Sports Medicine


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