Information on cost-effectiveness: An essential product of a national comparative effectiveness program

Neil Kirschner, Stephen G. Pauker, Joseph W. Stubbs, Mary M. Newman, Peter Basch, Yul D. Ejnes, Jeannine Z. Engel, Stephen D. Fihn, Susan H. Gunn, William R. Hersh, Michael D. Lahey, J. Leonard Lichtenfeld, Eric M. Mazur, Michael C. Sha

Research output: Contribution to journalReview articlepeer-review

99 Scopus citations


The American College of Physicians recently highlighted the need to provide increased information comparing the effectiveness of health care interventions to ensure the rational and effective practice of medicine. Comparative effectiveness refers to the evaluation of the relative clinical effectiveness, safety, and cost of 2 or more medical services, drugs, devices, therapies, or procedures used to treat the same condition. The College further recommended the establishment of an adequately funded, trusted national entity that should prioritize, sponsor, or produce both comparative clinical and cost-effectiveness data. This article addresses the need for the proposed entity to develop cost-effectiveness information. It examines the current reluctance to develop and use cost-effectiveness in the United States; it argues for the importance of this information for all health care stakeholders; and it makes specific recommendations regarding how this information can best be made available and used for the good of the public and our patients.

Original languageEnglish (US)
Pages (from-to)956-961
Number of pages6
JournalAnnals of internal medicine
Issue number12
StatePublished - Jun 17 2008

ASJC Scopus subject areas

  • Internal Medicine


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