Intermediate-Term Outcomes Following Transcatheter Aortic Valve Implantation in Patients with a History of Chest Radiation Therapy: A Propensity Score Matched Analysis

Kris Kumar, Mohammed Osman, Ashraf Samhan, Craig C. Morris, Trisha Chau, Tessa Herman, Gurion Lantz, Scott M. Chadderdon, Howard Song, Firas Zahr, Harsh Golwala

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Chest radiation therapy (XRT) has been associated with a higher rate of mortality following surgical aortic valve replacement. We performed a single-center retrospective analysis of patients with severe AS who underwent TAVI from January 1 2012 to July 31 2020 comparing patients with and without XRT. A total of 915 patients met inclusion criteria, with a total of 50 patients found to have a history of XRT. At a mean follow-up of 2.4 years, unadjusted and propensity score matching analysis demonstrated no differences in mortality, heart failure or bleeding-related hospitalization, overall stroke, and 30-day pacemaker implantation in patients with and without XRT.

Original languageEnglish (US)
Pages (from-to)E291-E293
JournalJournal of Invasive Cardiology
Volume35
Issue number6
DOIs
StatePublished - Jun 2023

Keywords

  • aortic stenosis
  • outcomes
  • radiation therapy
  • transcatheter aortic valve implantation

ASJC Scopus subject areas

  • General Medicine

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