TY - JOUR
T1 - Intestinal Failure
T2 - New Definition and Clinical Implications
AU - Kappus, Matthew
AU - Diamond, Sarah
AU - Hurt, Ryan T.
AU - Martindale, Robert
N1 - Publisher Copyright:
© 2016, Springer Science+Business Media New York.
PY - 2016/9/1
Y1 - 2016/9/1
N2 - Intestinal failure (IF) is a state in which the nutritional demands of the body are not met by the gastrointestinal absorptive surface. It is a long-recognized complication associated with short bowel syndrome, which results in malabsorption after significant resection of the intestine for many reasons or functional dysmotility. Etiologies have included Crohn’s disease, vascular complications, and the effects of radiation enteritis, as well as the effects of intestinal obstruction, dysmotility, or congenital defects. While IF has been long-recognized, it has historically not been uniformly defined, which has made both recognition and management challenging. This review examines the previous definitions of IF as well as the newer definition and classification of IF and how it is essential to IF clinical guidelines.
AB - Intestinal failure (IF) is a state in which the nutritional demands of the body are not met by the gastrointestinal absorptive surface. It is a long-recognized complication associated with short bowel syndrome, which results in malabsorption after significant resection of the intestine for many reasons or functional dysmotility. Etiologies have included Crohn’s disease, vascular complications, and the effects of radiation enteritis, as well as the effects of intestinal obstruction, dysmotility, or congenital defects. While IF has been long-recognized, it has historically not been uniformly defined, which has made both recognition and management challenging. This review examines the previous definitions of IF as well as the newer definition and classification of IF and how it is essential to IF clinical guidelines.
KW - Acute intestinal failure
KW - Chronic intestinal failure
KW - Home parenteral nutrition
KW - Intestinal failure
KW - Short bowel syndrome
KW - Short gut syndrome
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U2 - 10.1007/s11894-016-0525-x
DO - 10.1007/s11894-016-0525-x
M3 - Review article
C2 - 27447791
AN - SCOPUS:84979642617
SN - 1522-8037
VL - 18
JO - Current gastroenterology reports
JF - Current gastroenterology reports
IS - 9
M1 - 48
ER -