TY - JOUR
T1 - Intimate combination of low- and high-resolution image data
T2 - I. Real- space PET and 1H2O MRI, PETAMRI
AU - Sammi, Manoj K.
AU - Felder, Christoph A.
AU - Fowler, Joanna S.
AU - Lee, Jing Huei
AU - Levy, Alejandro V.
AU - Li, Xin
AU - Logan, Jean
AU - Pályka, Ildikó
AU - Rooney, William D.
AU - Volkow, Nora D.
AU - Wang, Gene Jack
AU - Springer, Charles S.
PY - 1999
Y1 - 1999
N2 - Two different types of (co-registered) images of the same slice of tissue will generally have different spatial resolutions. The judicious pixel-by-pixel combination of their data can be accomplished to yield a single image exhibiting properties of both. Here, axial 18FDG PET and 1H2O MR images of the human brain are used as the low- and high-resolution members of the pair. A color scale is necessary in order to provide for separate intensity parameters from the two image types. However, not all color scales can accommodate this separability. The HSV color model allows one to choose a color scale in which the intensity of the low-resolution image type is coded as hue, while that of the high-resolution type is coded as value, a reasonably independent parameter. Furthermore, the high- resolution image must have high contrast and be quantitative in the same sense as the low-resolution image almost always is. Here, relaxographic MR images (naturally segmented quantitative 1H2O spin-density components) are used. Their essentially complete contrast serves to effect an apparent editing function when encoded as the value of the color scale. Thus, the combination of 18FDG PET images with gray-matter (GM) relaxographic 1H2O images produces visually 'GM-edited' 18SFDG PETAMR (positron emission tomography and magnetic resonance) images. These exhibit the high sensitivity to tracer amounts characteristic of PET along with the high spatial resolution of 1H2O MRI. At the same time, however, they retain the complete quantitative measures of each of their basis images.
AB - Two different types of (co-registered) images of the same slice of tissue will generally have different spatial resolutions. The judicious pixel-by-pixel combination of their data can be accomplished to yield a single image exhibiting properties of both. Here, axial 18FDG PET and 1H2O MR images of the human brain are used as the low- and high-resolution members of the pair. A color scale is necessary in order to provide for separate intensity parameters from the two image types. However, not all color scales can accommodate this separability. The HSV color model allows one to choose a color scale in which the intensity of the low-resolution image type is coded as hue, while that of the high-resolution type is coded as value, a reasonably independent parameter. Furthermore, the high- resolution image must have high contrast and be quantitative in the same sense as the low-resolution image almost always is. Here, relaxographic MR images (naturally segmented quantitative 1H2O spin-density components) are used. Their essentially complete contrast serves to effect an apparent editing function when encoded as the value of the color scale. Thus, the combination of 18FDG PET images with gray-matter (GM) relaxographic 1H2O images produces visually 'GM-edited' 18SFDG PETAMR (positron emission tomography and magnetic resonance) images. These exhibit the high sensitivity to tracer amounts characteristic of PET along with the high spatial resolution of 1H2O MRI. At the same time, however, they retain the complete quantitative measures of each of their basis images.
UR - http://www.scopus.com/inward/record.url?scp=0032855313&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032855313&partnerID=8YFLogxK
U2 - 10.1002/(SICI)1522-2594(199908)42:2<345::AID-MRM17>3.0.CO;2-E
DO - 10.1002/(SICI)1522-2594(199908)42:2<345::AID-MRM17>3.0.CO;2-E
M3 - Article
C2 - 10440960
AN - SCOPUS:0032855313
SN - 0740-3194
VL - 42
SP - 345
EP - 360
JO - Magnetic Resonance in Medicine
JF - Magnetic Resonance in Medicine
IS - 2
ER -