Abstract
We report the magnetic resonance (MR) imaging characteristics of subdural osteoma and other benign calcified intracranial lesions to highlight imaging features that differentiate between these disease entities. A 63-year-old woman presented with progressively altered mental status. Non-contrast CT demonstrated a densely calcified right middle cranial fossa extra-axial mass. MR imaging of the lesion demonstrated T1 and T2 hypointensity without evidence of contrast enhancement, parenchymal abnormality, or connection to adjacent venous structures. Diffusion weighted imaging demonstrated markedly decreased signal intensity and artificially reduced diffusion on apparent diffusion coefficient map. Histologically, the tumor was predominantly composed of lamellar bone and small fragments of residual dura consistent with subdural osteoma. This case demonstrates that radiological examination can provide additional insight into the origin of intracranial osteomas (extradural versus subdural versus sinonasal) and help distinguish from other diagnostic considerations including benign meningeal ossification and calcified meningioma prior to surgical resection.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 263-266 |
| Number of pages | 4 |
| Journal | Journal of Neuroradiology |
| Volume | 39 |
| Issue number | 4 |
| DOIs | |
| State | Published - Oct 2012 |
| Externally published | Yes |
Funding
The first author thanks Bethany Barajas for her helpful comments regarding this manuscript. This work was supported by NS045013 and TL1 RR024129–01 from the National Center for Research Resources, a component of the National Institutes of Health (NIH) and NIH Roadmap for Medical Research.
| Funders | Funder number |
|---|---|
| Author National Institutes of Health National Institutes of Health National Institutes of Health National Institutes of Health The Bev Hartig Huntington's Disease Foundation National Institutes of Health | |
| National Institute of Neurological Disorders and Stroke | K23NS045013 |
| National Center for Research Resources |
Keywords
- Magnetic resonance imaging
- Meningioma
- Subdural osteoma
ASJC Scopus subject areas
- Radiological and Ultrasound Technology
- Radiology Nuclear Medicine and imaging
- Clinical Neurology
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