Intravenous agents and intraoperative neuroprotection: Beyond barbiturates

M. A. Cheng, M. A. Theard, R. Tempelhoff

Research output: Contribution to journalArticlepeer-review

57 Scopus citations


The authors discuss the role of intravenous anesthetic agents in brain protection. The newer intravenous anesthetics, etomidate and propofol, have been proposed as neuroprotective agents. Thiopental remains the drug of choice, however, for use prior to intraoperative ischemic events. The anesthetic ketamine presents surprising similarities to other N-methyl-D- aspartate receptor inhibitors, but remains controversial in its use in neurologically compromised patients.

Original languageEnglish (US)
Pages (from-to)185-199
Number of pages15
JournalCritical Care Clinics
Issue number1
StatePublished - 1997
Externally publishedYes

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine


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