Ivabradine in Post-operative Junctional Ectopic Tachycardia (JET): Breaking New Ground

Mani Ram Krishna, Mohammed Farooq Kunde, Raman Krishna Kumar, Seshadri Balaji

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


Junctional ectopic tachycardia (JET) is the commonest tachyarrhythmia in the early post-operative period in children undergoing open-heart surgery. It frequently leads to hemodynamic instability and needs to be managed aggressively. Amiodarone is the first-line agent along with non-pharmacological interventions. We report our initial experience with the use of Ivabradine in post-operative JET. A retrospective case records review of children with post-operative JET during the period from June 2018 to May 2019 was performed. Eight patients with post-operative JET were treated with Ivabradine during this period. The first patient was initially treated with Amiodarone. All eight patients responded to Ivabradine. The initial response was rate control permitting overdrive pacing. One patient had recurrence of JET 10 h after Ivabradine and after return to sinus rhythm. Amiodarone was administered along with the second dose of Ivabradine resulting in remission to sinus rhythm. Ivabradine appears to be an effective alternative to Amiodarone in children with post-operative JET based on our initial clinical experience.

Original languageEnglish (US)
Pages (from-to)1284-1288
Number of pages5
JournalPediatric Cardiology
Issue number6
StatePublished - Aug 15 2019


  • Anti-arrhythmic therapy
  • Funny current channel (I)
  • Post-operative arrhythmias

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Cardiology and Cardiovascular Medicine


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