Jugular foramen syndrome as a complication of metastatic melanoma

John M. Schweinfurth, Jonas T. Johnson, Jane Weissman

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


Introduction: The jugular foramen (Vernet) syndrome with neuropathy of cranial nerves IX-XI is more commonly due to metastatic lesions than primary neoplasms. Hypoglossal nerve involvement is referred to as the Collet Sicard variant of the jugular foramen syndrome. Materials and Methods: We report an elderly man who presents with dysphagia, dysarthira, hoarseness, and a 12-pound weight loss. Examination demonstrated paralysis of the right vagus and hypoglossal nerve. Communication and collaboration with the radiologist resulted in identification of the lesion. Computed tomographic (CT) guided needle aspiration confirmed metastatic melanoma. Discussion: The onset of cranial neuropathy may allow the site of lesion to be predicted based on knowledge of the cranial base and neural anatomy. Diagnostic evaluation is tailored to evaluate the area in question. Active, multidisciplinary collaboration is assential for success.

Original languageEnglish (US)
Pages (from-to)168-174
Number of pages7
JournalAmerican Journal of Otolaryngology--Head and Neck Medicine and Surgery
Issue number3
StatePublished - 1993
Externally publishedYes

ASJC Scopus subject areas

  • Otorhinolaryngology


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