Kinetic and Mechanistic Characterization of an Efficient Hydrolytic Antibody: Evidence for the Formation of an Acyl Intermediate

Medicine & Life Sciences

• Antibody Formation 71%
• Hydrolysis 60%
• Kinetics 57%
• Hydroxylamine 56%
• Esters 53%
• Antibodies 43%
• Methionine 27%
• Catalytic Antibodies 22%
• Organophosphonates 19%
• Catalysis 15%
• Phenol 15%
• Carbon 12%
• Catalytic Domain 11%
• Amino Acids 9%

Engineering & Materials Science

• Antibodies 100%
• Hydrolysis 79%
• Esters 57%
• Catalytic Antibodies 30%
• Enantiomers 22%
• Substrates 18%
• Catalysis 17%
• Phenols 16%
• Amino acids 15%
• Normal distribution 14%
• Carbon 9%

Chemical Compounds

• Hydroxylamine 50%
• Hydrolysis 48%
• Ester 28%
• Amino Acid Ester 20%
• Phosphonate 15%
• Rate-Determining Step 15%
• Velocity 13%
• Enantiomer 12%
• Phenol 11%
• Catalysis 10%