Levator palpebrae superioris fibre size in normals and patients with congenital ptosis

B. Edmunds, R. M. Manners, R. O. Weller, P. Steart, J. R.O. Collin

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


A study of the histochemical staining of levator palpebrae superioris (LPS) was undertaken to measure the muscle fibre size in normal individuals and in patients with congenital dystrophic ptosis in order to see whether there is an alteration in muscle fibre size in congenital ptosis. Eight LPS specimens were obtained: 4 from normal patients (3 from normal levator divided in a bilateral brow suspension procedure and 1 from an exenteration specimen) and 4 from levator resection procedures for treatment of unilateral congenital ptosis. Cryostat sections from these specimens were stained histochemically to reveal muscle fibre types. The orthogonal diameters were measuring using a computer-generated program and the two groups compared using the Mann-Whitney U-test. No statistically significant difference in muscle fibre diameter was found between normals and patients with congenital ptosis. There was also no change in the distribution or range of muscle fibre diameter in patients with congenital ptosis. Our findings do not support the classification of congenital ptosis as a dystrophy.

Original languageEnglish (US)
Pages (from-to)47-50
Number of pages4
Issue number1
StatePublished - Feb 1998
Externally publishedYes


  • Congenital dystrophic ptosis
  • Histochemistry
  • Levator palpebrae superioris

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems


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