Ligation of OX40 (CD134) regulates graft-versus-host disease (GVHD) and graft rejection in allogeneic bone marrow transplant recipients

Keyphrases

• Ligation 100%
• Graft-versus-host Disease (GvHD) 100%
• CD134 100%
• OX40 100%
• Allogeneic Bone Marrow Transplantation 100%
• Graft Rejection 100%
• Transplant Recipients 100%
• CD4+ 10%
• Activated T Cells 10%
• T Helper 2 10%
• Ligand Interactions 10%
• Monoclonal Antibody 5%
• B Cells 5%
• T Cells 5%
• CD8+ T Cells 5%
• CD8+ 5%
• Splenocytes 5%
• Transcriptional Repressor 5%
• Dendritic Cells 5%
• T-cell Mediated 5%
• Engraftment 5%
• Major Histocompatibility Complex 5%
• Signal Transducer 5%
• Disease-specific Mortality 5%
• Disease Reduction 5%
• Anti-OX40 5%
• N-donor Ligands 5%
• Ligand Regulation 5%
• Reduced Graft 5%
• Ligand Pathways 5%
• Alloresponse 5%
• CD28 Signaling 5%
• Activated Endothelial Cells 5%

Immunology and Microbiology

• Bone Marrow Transplantation 100%
• Graft-Versus-Host Disease 100%
• CD134 100%
• OX40L 100%
• T Cell 30%
• Cytotoxic T-Cell 20%
• Monoclonal Antibody 10%
• CD4 10%
• T-Helper Cell 10%
• Major Histocompatibility Complex 10%
• B Cell 10%
• Splenocyte 10%
• CD28 10%
• Dendritic Cell 10%
• Engraftment 10%
• STAT6 10%
• Endothelial Cells 10%