Lipoic acid, inflammation and diseases of the nervous system

Daniel W. Carr; Sonemany Salinthone

doi:10.1007/978-3-642-30018-9_86

Lipoic acid, inflammation and diseases of the nervous system

Daniel W. Carr, Sonemany Salinthone

Endocrinology, Diabetes and Clinical Nutrition

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

Oxidative stress and inflammation are normal biological processes that are implicated in the pathogenesis of many neurological diseases such as multiple sclerosis, cerebral ischemia, stroke, epilepsy, and diabetic neuropathy. Treatment with compounds that can block these processes has the potential to be therapeutically effective. Lipoic acid is a naturally occurring supplement that appears to act both as an antioxidant and an anti-inflammatory agent. This chapter reviews the current data on the effectiveness of LA for each of the above-mentioned diseases and also examines the possible mechanisms of actions that allow LA to function as a therapeutic agent.

Original language	English (US)
Title of host publication	Systems Biology of Free Radicals and Antioxidants
Publisher	Springer-Verlag Berlin Heidelberg
Pages	2349-2368
Number of pages	20
ISBN (Electronic)	9783642300189
ISBN (Print)	3642300170, 9783642300172
DOIs	https://doi.org/10.1007/978-3-642-30018-9_86
State	Published - May 1 2012

Keywords

Diabetic neuropathy
Inflammation
Lipoic acid
Multiple sclerosis
Oxidative stress
Stroke

ASJC Scopus subject areas

General Medicine

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10.1007/978-3-642-30018-9_86

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AB - Oxidative stress and inflammation are normal biological processes that are implicated in the pathogenesis of many neurological diseases such as multiple sclerosis, cerebral ischemia, stroke, epilepsy, and diabetic neuropathy. Treatment with compounds that can block these processes has the potential to be therapeutically effective. Lipoic acid is a naturally occurring supplement that appears to act both as an antioxidant and an anti-inflammatory agent. This chapter reviews the current data on the effectiveness of LA for each of the above-mentioned diseases and also examines the possible mechanisms of actions that allow LA to function as a therapeutic agent.

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Lipoic acid, inflammation and diseases of the nervous system

Abstract

Keywords

ASJC Scopus subject areas

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