Liver and renal disease

Thomas G. DeLoughery

doi:10.1007/978-3-319-09312-3_9

Liver and renal disease

Thomas G. DeLoughery

Knight Cancer Institute

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

This chapter discusses bleeding and thrombotic issues in patients with renal and liver disease. Causes, testing for, and management of both issues are discussed. While it has been accepted for years that patients with liver disease are at risk of bleeding, recently there has also been the realization that for most patients this hazard has been overstated and that paradoxically thrombosis may also be risk. Most bleeding in liver disease patients is due to mechanical reasons such as a ruptured varix rather than an underlying coagulopathy. In addition, classic tests of coagulation fail in many patients to fully assess their hemostatic capacity.

Original language	English (US)
Title of host publication	Hemostasis and Thrombosis, Third Edition
Publisher	Springer International Publishing
Pages	43-46
Number of pages	4
ISBN (Electronic)	9783319093123
ISBN (Print)	9783319093116
DOIs	https://doi.org/10.1007/978-3-319-09312-3_9
State	Published - Jan 1 2015

ASJC Scopus subject areas

Medicine(all)

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10.1007/978-3-319-09312-3_9

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AB - This chapter discusses bleeding and thrombotic issues in patients with renal and liver disease. Causes, testing for, and management of both issues are discussed. While it has been accepted for years that patients with liver disease are at risk of bleeding, recently there has also been the realization that for most patients this hazard has been overstated and that paradoxically thrombosis may also be risk. Most bleeding in liver disease patients is due to mechanical reasons such as a ruptured varix rather than an underlying coagulopathy. In addition, classic tests of coagulation fail in many patients to fully assess their hemostatic capacity.

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Liver and renal disease

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