Abstract
Using3H-prazosin, we have examined the distribution of α1-adrenergic receptors in the supraoptic and paraventricular nuclei of the human hypothalamus. Our studies show that binding sites for3H-prazosin in human hypothalamus possess pharmacological characteristics similar to those of rat brain. Autoradiographic studies revealed discrete localization of3H-prazosin to the paraventricular and supraoptic nuclei.
Original language | English (US) |
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Pages (from-to) | 315-319 |
Number of pages | 5 |
Journal | Neuroendocrinology |
Volume | 51 |
Issue number | 3 |
DOIs | |
State | Published - 1990 |
Externally published | Yes |
Keywords
- Human hypothalamus
- Paraventricular nucleus
- Prazosin
- Supraoptic nucleus
- α-Receptors
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Endocrinology
- Endocrine and Autonomic Systems
- Cellular and Molecular Neuroscience