Long-term risks of bladder augmentation in pediatric patients

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53 Scopus citations


PURPOSE OF REVIEW: Bladder augmentation is still a commonly performed reconstructive procedure for pediatric patients with severe bladder dysfunction. Recent developments in the long-term risks associated with this procedure are reviewed. RECENT FINDINGS: There are metabolic changes in these patients after incorporation of bowel into the urinary tract. Linear growth and bone mineral density are more affected by the primary disorder rather than bladder augmentation. There is a high rate of reoperation in patients after bladder augmentation for perforation, bladder stones, and bowel obstruction. Bladder cancer has been reported in patients after bladder augmentation but also in patients without augmentation. SUMMARY: Bladder augmentation is associated with a number of potential long-term risks, including a high risk of needing further surgery and development of serious complications such as bowel obstruction or bladder perforation. Bladder stones continue to be common in patients after bladder augmentation. Multiple cases of bladder cancer have been reported recently in young adults with a history of bladder augmentation in childhood and reinforce the need for lifelong follow up for these patients. Future studies will hopefully define the benefits and role of cancer surveillance for these patients.

Original languageEnglish (US)
Pages (from-to)408-412
Number of pages5
JournalCurrent Opinion in Urology
Issue number4
StatePublished - Jul 2008
Externally publishedYes


  • Bladder augmentation
  • Bladder cancer
  • Bladder exstrophy
  • Bladder stones
  • Spina bifida

ASJC Scopus subject areas

  • Urology


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