Longitudinal study of bone density and periodontal disease in men

K. R. Phipps, B. K.S. Chan, T. E. Madden, N. C. Geurs, M. S. Reddy, C. E. Lewis, E. S. Orwoll

Research output: Contribution to journalArticlepeer-review

45 Scopus citations


Bone loss is a feature of both periodontitis and osteoporosis, and periodontal destruction may be influenced by systemic bone loss. This study evaluated the association between periodontal disease and bone mineral density (BMD) in a cohort of 1347 (137 edentulous) older men followed for an average of 2.7 years. Participants were recruited from the Osteoporotic Fractures in Men Study. Random half-mouth dental measures included clinical attachment loss (CAL), pocket depth (PD), calculus, plaque, and bleeding. BMD was measured at the hip, spine, and whole-body, by dual-energy x-ray absorptiometry, and at the heel by ultrasound. After adjustment for age, smoking, race, education, body mass index, and calculus, there was no association between number of teeth, periodontitis, periodontal disease progression, and either BMD or annualized rate of BMD change. We found little evidence of an association between periodontitis and skeletal BMD among older men.

Original languageEnglish (US)
Pages (from-to)1110-1114
Number of pages5
JournalJournal of dental research
Issue number11
StatePublished - Nov 2007


  • Epidemiology
  • Men
  • Osteoporosis
  • Periodontal disease

ASJC Scopus subject areas

  • Dentistry(all)


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