Abstract
Chromatographic and magnetic resonance spectroscopic measurements of thiol reduction-oxidation state in chemically constructed samples show close analytical agreement. This result, coupled with the synthesis of new probe molecules allowing greater sensitivity and lower toxicity, supports the development of an NMR method for non-invasive thiol redox measurement, an important variable in the response of tumors to radiation and chemotherapy.
Original language | English (US) |
---|---|
Pages (from-to) | 755-757 |
Number of pages | 3 |
Journal | International Journal of Radiation Oncology, Biology, Physics |
Volume | 22 |
Issue number | 4 |
DOIs | |
State | Published - 1992 |
Externally published | Yes |
Keywords
- Nuclear magnetic resonance spectroscopy
- Reduction-oxidation state
- Thiols
ASJC Scopus subject areas
- Radiation
- Oncology
- Radiology Nuclear Medicine and imaging
- Cancer Research