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Matrix metalloproteinases and the development of cancer

Research output: Contribution to journalReview articlepeer-review

Abstract

Proteolytic remodeling of the extracellular matrix is an important aspect of the creation and progression of cancer. Matrix metalloproteinases are important at several points during multistage neoplastic progression in tumor cells and responding blood vessels, inflammatory cells and stroma.

Original languageEnglish (US)
Pages (from-to)895-904
Number of pages10
JournalChemistry and Biology
Volume3
Issue number11
DOIs
StatePublished - 1996
Externally publishedYes

Funding

We acknowledge all the scientists who made contributions to the areas of research reviewed here that we could not cite due to space constraints. This work was supported in part by funds from the National Institutes of Health (CA 09043) to LMC, and (CA 57621 and CA52071 to ZW.

FundersFunder number
Author National Institutes of Health National Institutes of Health National Institutes of Health National Institutes of Health The Bev Hartig Huntington's Disease Foundation National Institutes of HealthCA52071, CA 09043
National Institute of Health-National Cancer InstituteR01CA057621

    ASJC Scopus subject areas

    • Biochemistry
    • Molecular Medicine
    • Molecular Biology
    • Pharmacology
    • Drug Discovery
    • Clinical Biochemistry

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