Medications for Managing Preexisting and Gestational Diabetes in Pregnancy

Michaela Rickert, Aaron B. Caughey, Amy M. Valent

Research output: Contribution to journalReview articlepeer-review


Persons with gestational and pregestational diabetes during pregnancy may require pharmacologic agents to achieve pregnancy glycemic targets, and the available medications for use in pregnancy are limited. Insulin is the only FDA-approved medication for use in pregnancy and has the greatest evidence for safety and efficacy. Metformin and glyburide are the most commonly used oral agents in pregnancy. Understanding each medication's unique pharmacokinetics, potential side effects, fetal or childhood risks, gestational age of medication initiation and patient's diabetes care barriers are important aspects of shared decision-making and choosing a regimen that will achieve glycemic and pregnancy goals.

Original languageEnglish (US)
Pages (from-to)121-136
Number of pages16
JournalObstetrics and Gynecology Clinics of North America
Issue number1
StatePublished - Mar 2023


  • Acarbose
  • Diabetes and breastfeeding
  • Diabetes and pregnancy
  • Glyburide
  • Insulin
  • Medications and pregnancy
  • Metformin
  • Pregnancy

ASJC Scopus subject areas

  • Obstetrics and Gynecology


Dive into the research topics of 'Medications for Managing Preexisting and Gestational Diabetes in Pregnancy'. Together they form a unique fingerprint.

Cite this