Abstract
Persons with gestational and pregestational diabetes during pregnancy may require pharmacologic agents to achieve pregnancy glycemic targets, and the available medications for use in pregnancy are limited. Insulin is the only FDA-approved medication for use in pregnancy and has the greatest evidence for safety and efficacy. Metformin and glyburide are the most commonly used oral agents in pregnancy. Understanding each medication's unique pharmacokinetics, potential side effects, fetal or childhood risks, gestational age of medication initiation and patient's diabetes care barriers are important aspects of shared decision-making and choosing a regimen that will achieve glycemic and pregnancy goals.
Original language | English (US) |
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Pages (from-to) | 121-136 |
Number of pages | 16 |
Journal | Obstetrics and Gynecology Clinics of North America |
Volume | 50 |
Issue number | 1 |
DOIs | |
State | Published - Mar 2023 |
Keywords
- Acarbose
- Diabetes and breastfeeding
- Diabetes and pregnancy
- Glyburide
- Insulin
- Medications and pregnancy
- Metformin
- Pregnancy
ASJC Scopus subject areas
- Obstetrics and Gynecology