TY - JOUR
T1 - Microbial DNA testing for inflammatory diseases of the brain of uncertain etiology
AU - Takahashi, Courtney
AU - Mass, Michele
AU - Hamilton, Bronwyn
AU - Humayun Guletkin, Satir
AU - Bourdette, Dennis
PY - 2014/6
Y1 - 2014/6
N2 - Neurologists may be confronted with patients who present with inflammatory brain lesions where the diagnosis cannot be made through history and physical examination alone. Molecular testing for bacterial infections, tuberculosis, and fungal infections may aid in the diagnosis. Since the treatments for these disorders are different and delays can result in permanent neurologic disability and death, rapid and accurate diagnoses are critical. This review provides the neurologist with testing options and recommends ways to enhance sensitivity and specificity.
AB - Neurologists may be confronted with patients who present with inflammatory brain lesions where the diagnosis cannot be made through history and physical examination alone. Molecular testing for bacterial infections, tuberculosis, and fungal infections may aid in the diagnosis. Since the treatments for these disorders are different and delays can result in permanent neurologic disability and death, rapid and accurate diagnoses are critical. This review provides the neurologist with testing options and recommends ways to enhance sensitivity and specificity.
UR - http://www.scopus.com/inward/record.url?scp=84902687200&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84902687200&partnerID=8YFLogxK
U2 - 10.1212/CPJ.0000000000000021
DO - 10.1212/CPJ.0000000000000021
M3 - Article
AN - SCOPUS:84902687200
SN - 2163-0402
VL - 4
SP - 192
EP - 198
JO - Neurology: Clinical Practice
JF - Neurology: Clinical Practice
IS - 3
ER -