MMP9 potentiates pulmonary metastasis formation

Léon C.L. Van Kempen; Lisa M. Coussens

doi:10.1016/S1535-6108(02)00157-5

MMP9 potentiates pulmonary metastasis formation

Léon C.L. Van Kempen
, Lisa M. Coussens

Research output: Contribution to journal › Review article › peer-review

154 Scopus citations

Abstract

Tumor cell dissemination to distant organ sites is a complex process involving multiple cell types, soluble growth factors, adhesion receptors, and tissue remodeling. A new study in this issue of Cancer Cell shows that MMP9-expressing tumor-associated macrophages play a key role in prepping premetastatic sites for eventual malignant cell growth in a manner dependent upon vascular endothelial growth factor receptor-1 (VEGFR-1).

Original language	English (US)
Pages (from-to)	251-252
Number of pages	2
Journal	Cancer Cell
Volume	2
Issue number	4
DOIs	https://doi.org/10.1016/S1535-6108(02)00157-5
State	Published - Oct 2002
Externally published	Yes

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1016/S1535-6108(02)00157-5

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@article{673b54e3510e4f9aa6afa44204fb623d,

title = "MMP9 potentiates pulmonary metastasis formation",

abstract = "Tumor cell dissemination to distant organ sites is a complex process involving multiple cell types, soluble growth factors, adhesion receptors, and tissue remodeling. A new study in this issue of Cancer Cell shows that MMP9-expressing tumor-associated macrophages play a key role in prepping premetastatic sites for eventual malignant cell growth in a manner dependent upon vascular endothelial growth factor receptor-1 (VEGFR-1).",

author = "\{Van Kempen\}, \{L{\'e}on C.L.\} and Coussens, \{Lisa M.\}",

year = "2002",

month = oct,

doi = "10.1016/S1535-6108(02)00157-5",

language = "English (US)",

volume = "2",

pages = "251--252",

journal = "Cancer Cell",

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publisher = "Cell Press",

number = "4",

}

TY - JOUR

T1 - MMP9 potentiates pulmonary metastasis formation

AU - Van Kempen, Léon C.L.

AU - Coussens, Lisa M.

PY - 2002/10

Y1 - 2002/10

N2 - Tumor cell dissemination to distant organ sites is a complex process involving multiple cell types, soluble growth factors, adhesion receptors, and tissue remodeling. A new study in this issue of Cancer Cell shows that MMP9-expressing tumor-associated macrophages play a key role in prepping premetastatic sites for eventual malignant cell growth in a manner dependent upon vascular endothelial growth factor receptor-1 (VEGFR-1).

AB - Tumor cell dissemination to distant organ sites is a complex process involving multiple cell types, soluble growth factors, adhesion receptors, and tissue remodeling. A new study in this issue of Cancer Cell shows that MMP9-expressing tumor-associated macrophages play a key role in prepping premetastatic sites for eventual malignant cell growth in a manner dependent upon vascular endothelial growth factor receptor-1 (VEGFR-1).

UR - https://www.scopus.com/pages/publications/0036781709

UR - https://www.scopus.com/pages/publications/0036781709#tab=citedBy

U2 - 10.1016/S1535-6108(02)00157-5

DO - 10.1016/S1535-6108(02)00157-5

M3 - Review article

C2 - 12398887

AN - SCOPUS:0036781709

SN - 1535-6108

VL - 2

SP - 251

EP - 252

JO - Cancer Cell

JF - Cancer Cell

IS - 4

ER -

MMP9 potentiates pulmonary metastasis formation

Abstract

ASJC Scopus subject areas

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