Model Selection

D. L. Hickman, S. Putta, N. A. Johnston, K. D. Prongay

    Research output: Chapter in Book/Report/Conference proceedingChapter


    When designing a research plan for the exploration of a scientific hypothesis, it is critical to evaluate all available models, including in vitro and in vivo options, to ensure selection of the most appropriate model to yield the best information. Animal models are one tool that is used to support research, but in vitro and human models are also extremely valuable. This chapter will introduce concepts key to the selection of an animal model and an overview of the types of animal models that are available.

    Original languageEnglish (US)
    Title of host publicationPrinciples of Animal Research for Graduate and Undergraduate Students
    PublisherElsevier Inc.
    Number of pages24
    ISBN (Electronic)9780128023662
    ISBN (Print)9780128021514
    StatePublished - 2017


    • 3 R's
    • Animal model
    • Behavioral models
    • Chemically induced models
    • Genetically manipulated models
    • Physically induced models
    • Production models
    • Random mutation models
    • Spontaneous animal models
    • Surgical models

    ASJC Scopus subject areas

    • Medicine(all)


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