Model Selection

D. L. Hickman; S. Putta; N. A. Johnston; K. D. Prongay

doi:10.1016/B978-0-12-802151-4.00006-2

Model Selection

D. L. Hickman, S. Putta, N. A. Johnston, K. D. Prongay

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

When designing a research plan for the exploration of a scientific hypothesis, it is critical to evaluate all available models, including in vitro and in vivo options, to ensure selection of the most appropriate model to yield the best information. Animal models are one tool that is used to support research, but in vitro and human models are also extremely valuable. This chapter will introduce concepts key to the selection of an animal model and an overview of the types of animal models that are available.

Original language	English (US)
Title of host publication	Principles of Animal Research for Graduate and Undergraduate Students
Publisher	Elsevier Inc.
Pages	93-116
Number of pages	24
ISBN (Electronic)	9780128023662
ISBN (Print)	9780128021514
DOIs	https://doi.org/10.1016/B978-0-12-802151-4.00006-2
State	Published - 2017

Keywords

3 R's
Animal model
Behavioral models
Chemically induced models
Genetically manipulated models
Physically induced models
Production models
Random mutation models
Spontaneous animal models
Surgical models

ASJC Scopus subject areas

Medicine(all)

Access to Document

10.1016/B978-0-12-802151-4.00006-2

Cite this

@inbook{3da7383294dd46dda0d7c7035cac8ee4,

title = "Model Selection",

abstract = "When designing a research plan for the exploration of a scientific hypothesis, it is critical to evaluate all available models, including in vitro and in vivo options, to ensure selection of the most appropriate model to yield the best information. Animal models are one tool that is used to support research, but in vitro and human models are also extremely valuable. This chapter will introduce concepts key to the selection of an animal model and an overview of the types of animal models that are available.",

keywords = "3 R's, Animal model, Behavioral models, Chemically induced models, Genetically manipulated models, Physically induced models, Production models, Random mutation models, Spontaneous animal models, Surgical models",

author = "Hickman, {D. L.} and S. Putta and Johnston, {N. A.} and Prongay, {K. D.}",

year = "2017",

doi = "10.1016/B978-0-12-802151-4.00006-2",

language = "English (US)",

isbn = "9780128021514",

pages = "93--116",

booktitle = "Principles of Animal Research for Graduate and Undergraduate Students",

publisher = "Elsevier Inc.",

}

TY - CHAP

T1 - Model Selection

AU - Hickman, D. L.

AU - Putta, S.

AU - Johnston, N. A.

AU - Prongay, K. D.

PY - 2017

Y1 - 2017

N2 - When designing a research plan for the exploration of a scientific hypothesis, it is critical to evaluate all available models, including in vitro and in vivo options, to ensure selection of the most appropriate model to yield the best information. Animal models are one tool that is used to support research, but in vitro and human models are also extremely valuable. This chapter will introduce concepts key to the selection of an animal model and an overview of the types of animal models that are available.

AB - When designing a research plan for the exploration of a scientific hypothesis, it is critical to evaluate all available models, including in vitro and in vivo options, to ensure selection of the most appropriate model to yield the best information. Animal models are one tool that is used to support research, but in vitro and human models are also extremely valuable. This chapter will introduce concepts key to the selection of an animal model and an overview of the types of animal models that are available.

KW - 3 R's

KW - Animal model

KW - Behavioral models

KW - Chemically induced models

KW - Genetically manipulated models

KW - Physically induced models

KW - Production models

KW - Random mutation models

KW - Spontaneous animal models

KW - Surgical models

UR - http://www.scopus.com/inward/record.url?scp=85032368846&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85032368846&partnerID=8YFLogxK

U2 - 10.1016/B978-0-12-802151-4.00006-2

DO - 10.1016/B978-0-12-802151-4.00006-2

M3 - Chapter

AN - SCOPUS:85032368846

SN - 9780128021514

SP - 93

EP - 116

BT - Principles of Animal Research for Graduate and Undergraduate Students

PB - Elsevier Inc.

ER -

Model Selection

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this