Modeling the dynamic composition of engineered cartilage

Christopher G. Wilson, Sean S. Kohles, Lawrence J. Bonassar

Research output: Contribution to journalConference articlepeer-review


Investigation of the mechanisms underlying scaffold degradation and neotissue synthesis is essential to understanding the mechanical and biological performance of engineered tissues. Modeling the dynamic composition of cell-polymer constructs may be useful in estimating the constructs' long-term function. In this preliminary study, we identified potential mechanisms and developed mathematical models to describe scaffold mass loss and extracellular matrix synthesis for engineered cartilage.

Original languageEnglish (US)
Pages (from-to)15-16
Number of pages2
JournalAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
StatePublished - 2001
Externally publishedYes
Event2001 ASME International Mechanical Engineering Congress and Exposition - New York, NY, United States
Duration: Nov 11 2001Nov 16 2001

ASJC Scopus subject areas

  • Engineering(all)


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