TY - JOUR
T1 - Modulation of transmitter release at giant synapses of the auditory system
AU - Trussell, Laurence O.
PY - 2002/8/1
Y1 - 2002/8/1
N2 - The relay nuclei of the auditory brainstem contain some of the largest nerve terminals in the mammalian brain. Endbulb and calyceal synapses convey signals with a high degree of precision and reliability. However, recent studies reveal that these synapses possess numerous and remarkably diverse mechanisms for the modulation of transmitter release. The implication is that successful relay of signals in vivo may require the ability to fine-tune synaptic transmission.
AB - The relay nuclei of the auditory brainstem contain some of the largest nerve terminals in the mammalian brain. Endbulb and calyceal synapses convey signals with a high degree of precision and reliability. However, recent studies reveal that these synapses possess numerous and remarkably diverse mechanisms for the modulation of transmitter release. The implication is that successful relay of signals in vivo may require the ability to fine-tune synaptic transmission.
UR - http://www.scopus.com/inward/record.url?scp=0036685441&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036685441&partnerID=8YFLogxK
U2 - 10.1016/S0959-4388(02)00335-5
DO - 10.1016/S0959-4388(02)00335-5
M3 - Review article
C2 - 12139987
AN - SCOPUS:0036685441
SN - 0959-4388
VL - 12
SP - 400
EP - 404
JO - Current Opinion in Neurobiology
JF - Current Opinion in Neurobiology
IS - 4
ER -