Monitoring intracranial pressure

Andrea Orfanakis, Ansgar Brambrink

Research output: Chapter in Book/Report/Conference proceedingChapter


The cranium is uniquely intolerant to changes in volume. The classical thinking of the relationship between components of the cranium and the pressure created by their presence is defined by the Monroe Kellie Doctrine [1]. Under normal physiologic conditions tissue cells, blood, and cerebrospinal fluid (CSF) maintain a consistent presence within the cranium and spinal cord areas. When any single component increases, the other two have a limited capacity to accommodate by shifting into accessory spaces so as to avoid a rise in intracranial pressure (ICP) and thus maintain stable cerebral perfusion pressure (CPP).

Original languageEnglish (US)
Title of host publicationMonitoring the Nervous System for Anesthesiologists and Other Health Care Professionals
PublisherSpringer US
Number of pages13
ISBN (Electronic)9781461403081
ISBN (Print)1461403073, 9781461403074
StatePublished - Nov 1 2012
Externally publishedYes


  • Cerebral pressure reactivity
  • Coagulopathy
  • Herniation
  • Intracranial pressure monitoring
  • Intraventricular catheter
  • Monro-Kellie hypothesis
  • Parenchymal devices

ASJC Scopus subject areas

  • Medicine(all)


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