Abstract
The cranium is uniquely intolerant to changes in volume. The classical thinking of the relationship between components of the cranium and the pressure created by their presence is defined by the Monroe Kellie Doctrine [1]. Under normal physiologic conditions tissue cells, blood, and cerebrospinal fluid (CSF) maintain a consistent presence within the cranium and spinal cord areas. When any single component increases, the other two have a limited capacity to accommodate by shifting into accessory spaces so as to avoid a rise in intracranial pressure (ICP) and thus maintain stable cerebral perfusion pressure (CPP).
Original language | English (US) |
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Title of host publication | Monitoring the Nervous System for Anesthesiologists and Other Health Care Professionals |
Publisher | Springer US |
Pages | 279-291 |
Number of pages | 13 |
Volume | 9781461403081 |
ISBN (Electronic) | 9781461403081 |
ISBN (Print) | 1461403073, 9781461403074 |
DOIs | |
State | Published - Nov 1 2012 |
Externally published | Yes |
Keywords
- Cerebral pressure reactivity
- Coagulopathy
- Herniation
- Intracranial pressure monitoring
- Intraventricular catheter
- Monro-Kellie hypothesis
- Parenchymal devices
ASJC Scopus subject areas
- Medicine(all)