@inproceedings{3b056b752318456d94ee6554082ee796,
title = "Monitoring of tissue perfusion during esophagectomies with optical fiber probe spectroscopy",
abstract = "The specific optical spectra of tissues contain information about the biochemical composition. We present a simple optical fiber probe spectrometer design for noninvasive measurement of oxygen saturation in the microvasculature of stomach tissue. In a human Esophagectomy model with 23 patients, we measured the spectrum following surgical ligation of two of the three arterial paths to the stomach tissue that will become the anastamosis. Combining a diffusion model for semi-infinite slab remittance with absorption spectroscopy, we are able to specify the ratio of oxy-hemoglobin to deoxy-hemoglobin present in the tissue. We show a resting state of 0.47 (oxy-hemaglobin/total-hemaglobin) saturation decrease of 29% (p < 0.01) when arterial supply is reduced by artery ligation.",
author = "Dan Gareau and John Hunter and Steven Jacques",
year = "2010",
doi = "10.1117/12.843705",
language = "English (US)",
isbn = "9780819479518",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Advanced Biomedical and Clinical Diagnostic Systems VIII",
note = "Advanced Biomedical and Clinical Diagnostic Systems VIII ; Conference date: 24-01-2010 Through 26-01-2010",
}