Morphologic effects of contact lens wear on the corneal surface

W. D. Mathers, M. S. Sachdev, M. Petroll, M. A. Lemp

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


We used specular microscopy of the corneal epithelium to examine 29 eyes of 29 patients each wearing one of five different types of contact lenses. We compared these with 24 eyes of 24 age-matched control patients. We found patients with aphakic extended wear soft contact lenses had significantly larger cells (818 ± 186 μm2) than all other groups; and they were significantly larger than their age-matched control group (573 ± 174 μm2)(P <.002). The epithelial cells of extended wear soft contact lens patients (609 ± 97 μm2) and daily wear rigid gas permeable contact lens patients (613 ± 103 μm2) were larger than their control group of normal young patients (513 ± 53 μm2). The cells of daily wear soft contact lens patients (484 ± 111 μm2) and hard contact lens patients (517 ± 46 μm2), however, were not different from controls. This study domonstrates a statistically significant shift in mean cell area of corneal epithelial cells in patients wearing some types of contact lenses.

Original languageEnglish (US)
Pages (from-to)49-52
Number of pages4
JournalCLAO Journal
Issue number1
StatePublished - 1992
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology


Dive into the research topics of 'Morphologic effects of contact lens wear on the corneal surface'. Together they form a unique fingerprint.

Cite this