Multiple sclerosis and vitamin D: A review and recommendations

Andrew J. Solomon, Ruth H. Whitham

Research output: Contribution to journalArticlepeer-review

27 Scopus citations


A relationship between vitamin D and several diseases, including multiple sclerosis (MS), has recently received interest in the scientific community. Vitamin D appears to have important actions beyond endocrine function, particularly for the immune system. Risk of development of MS, as well as disease severity, has been associated with vitamin D in a variety of studies. There remains a need for prospective studies to further establish this relationship. Given the current evidence of the potential benefits of vitamin D, it appears to be reasonable and safe to consider vitamin D supplementation at dosing adequate to achieve normal levels in patients with MS and clinically isolated syndrome.

Original languageEnglish (US)
Pages (from-to)389-396
Number of pages8
JournalCurrent neurology and neuroscience reports
Issue number5
StatePublished - Sep 2010
Externally publishedYes


  • 1,25-dihydroxyvitamin D
  • 25-hydroxyvitamin D
  • Deficiency
  • Demyelinating
  • Multiple sclerosis
  • Prevention
  • Review
  • Vitamin D

ASJC Scopus subject areas

  • General Neuroscience
  • Clinical Neurology


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