Mutagenic spectra arising from replication bypass of the 2,6-diamino-4-hydroxy-N⁵-methyl formamidopyrimidine adduct in primate cells

Medicine & Life Sciences

• N6-(2-deoxypentofuranosyl)-2,6-diamino-3,4-dihydro-4-oxo-5-N-methylformamidopyrimidine 100%
• Primates 38%
• Nucleotides 13%
• Genetic Vectors 10%
• hydroxide ion 9%
• DNA-Directed DNA Polymerase 9%
• DNA Replication 8%
• Mutagenesis 8%
• Phenotype 5%
• Mutation 4%
• DNA 4%
• Animals 4%
• In Vitro Techniques 3%

Chemical Compounds

• Formamidopyrimidine 69%
• Adduct 29%
• Mutagenic Agent 16%
• Standard Model 15%
• Modification 11%
• Nucleobase 11%
• Dinucleotide 11%
• Mutation 8%
• Nucleotide 8%
• Hydroxide 8%
• Substitution Reaction 6%
• Reaction Yield 4%
• Ion 4%