Mutations in FLVCR1 cause posterior column ataxia and retinitis pigmentosa

Keyphrases

• Cell Surface Receptor 100%
• Receptor 1 100%
• Retinitis pigmentosa 100%
• Feline Leukemia Virus (FeLV) 100%
• Virus Subgroup 100%
• Posterior Column Ataxia 100%
• Spinal Cord 60%
• Retina 60%
• Posterior Column 60%
• Proprioception 40%
• Neural Signals 40%
• FLVCR1 40%
• Transporter Proteins 20%
• Molecular Mechanism 20%
• Brain Regions 20%
• Quantitative PCR 20%
• Wild Mice 20%
• Dysregulation 20%
• Cellular Mechanisms 20%
• Autosomal Recessive 20%
• Iron Homeostasis 20%
• Single-family 20%
• Common Mechanisms 20%
• Sanger Sequencing 20%
• Sensory Modality 20%
• Homozygous Missense mutation 20%
• Heme Transporter 20%
• Heme Homeostasis 20%
• Bioinformatic Filtering 20%
• High-throughput Sequencing 20%
• Coding Variants 20%
• Channel Segments 20%
• Inherited Retinal Disease 20%
• Single nucleotide 20%
• Transmembrane Channel 20%
• Integrated Bioinformatics Analysis 20%
• DNA Capture 20%
• Real-time Quantification 20%
• Pathologic Features 20%
• Gene Encoding 20%

Neuroscience

• Ataxia 100%
• Retinitis pigmentosa 100%
• Posterior Column 100%
• Receptor 100%
• Spinal Cord 37%
• Proprioception 25%
• Heme 25%
• Messenger RNA 25%
• Missense Mutation 12%
• Retinal Disease 12%
• Transmembrane Protein 12%
• Autosomal Recessive Disorder 12%
• Mutated Genes 12%
• Carrier Protein 12%
• Reverse Transcription Polymerase Chain Reaction 12%
• Brain Region 12%
• Dideoxynucleotide Sequencing 12%
• Chromosome 12%
• Sensory Modality 12%