Myosin-VIIa and transduction channel tension

P. G. Gillespie

doi:10.1038/nn0102-3

Myosin-VIIa and transduction channel tension

P. G. Gillespie

Otolaryngology

Research output: Contribution to journal › Short survey › peer-review

13 Scopus citations

Abstract

Hair cells of the ear transduce sound via a mechanical link between hair bundle movement and channel gating, which is under tension at rest. A new paper reports that myosin-VIIa is critical for maintaining resting force on the link, explaining why mutations of this gene cause deafness.

Original language	English (US)
Pages (from-to)	3-4
Number of pages	2
Journal	Nature Neuroscience
Volume	5
Issue number	1
DOIs	https://doi.org/10.1038/nn0102-3
State	Published - Jan 15 2002

ASJC Scopus subject areas

Neuroscience(all)

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10.1038/nn0102-3

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abstract = "Hair cells of the ear transduce sound via a mechanical link between hair bundle movement and channel gating, which is under tension at rest. A new paper reports that myosin-VIIa is critical for maintaining resting force on the link, explaining why mutations of this gene cause deafness.",

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Myosin-VIIa and transduction channel tension

Abstract

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