Neutropenic Enterocolitis

Research output: Contribution to journalReview articlepeer-review

20 Scopus citations


Neutropenic enterocolitis, also known as typhlitis or ileocecal syndrome, is a rare but important complication of neutropenia associated with malignancy. It occurs as a result of chemotherapeutic damage to the intestinal mucosa in the context of an absolute neutropenia, and can rapidly progress to intestinal perforation, multisystem organ failure, and sepsis. Presenting signs and symptoms may include fever, abdominal pain, nausea, vomiting, and diarrhea. Rapid identification by emergency physicians and timely, aggressive medical and/or surgical intervention are the cornerstones of survival for these patients.

Original languageEnglish (US)
Pages (from-to)415-422
Number of pages8
JournalEmergency Medicine Clinics of North America
Issue number3
StatePublished - Aug 2009


  • Cancer
  • Chemotherapy
  • Enterocolitis
  • Fever
  • Neutropenia
  • Typhlitis

ASJC Scopus subject areas

  • Emergency Medicine


Dive into the research topics of 'Neutropenic Enterocolitis'. Together they form a unique fingerprint.

Cite this