No additional benefit of using a calcium hydroxide liner during stepwise caries removal: A randomized clinical trial

Maria Auxiliadora Pereira, Reginaldo Batista dos Santos-Júnior, Johnny Alexandre Tavares, Alaíde Hermínia Oliveira, Pollyana Caldeira Leal, Wilton Mitsunari Takeshita, Antônio Márcio Barbosa-Júnior, Luiz Eduardo Braga Bertassoni, André Luis Faria-e-Silva

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


Background Clinicians often use calcium hydroxide liners during stepwise treatment of advanced caries. In this randomized clinical trial, the authors compared the short-term outcome of stepwise caries removal with and without use of a calcium hydroxide liner in conjunction with provisional resin-modified glass ionomer (RMGI) restorations. Methods The authors included in the trial 98 patients aged 15 to 30 years who had a deep carious lesion in a posterior tooth. The authors measured the dentin thickness radiographically and recorded its color, consistency, and moisture, as well as the bacterial count of the lesions. After partial caries removal, the authors assigned patients randomly to have their caries provisionally restored using RMGI with (control group) or without (test group) a calcium hydroxide liner. The primary outcome measure was tooth vitality after 90 days. Secondary outcomes included changes in dentinal, radiographic, and microbiological characteristics of the lesions. Results The authors found no statistically significant difference between the test and control groups in tooth vitality after 90 days. Irrespective of calcium hydroxide liner use, the authors observed darker, harder, drier, and less contaminated dentin after the provisional restorations, but dentin thickness remained unchanged. Conclusions On the basis of this 3-month clinical trial's results, the use of a calcium hydroxide liner during stepwise caries excavation and provisional restoration did not provide any additional benefit. Practical Implications After 3 months, using a calcium hydroxide liner does not appear to offer any additional benefit when clinicians use RMGI provisional restorations during stepwise caries removal. Longer studies are needed to confirm these results.

Original languageEnglish (US)
Pages (from-to)369-376
Number of pages8
JournalJournal of the American Dental Association
Issue number6
StatePublished - Jun 2017


  • Randomized controlled clinical trials
  • caries
  • glass ionomer cements

ASJC Scopus subject areas

  • General Dentistry


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