Abstract
The present paper introduces a numerical calibration method for the easy and practical implementation of multiple spectrometer-based spectral-domain optical coherence tomography (SD-OCT) systems. To address the limitations of the traditional hardware-based spectrometer alignment across more than one spectrometer, we applied a numerical spectral calibration algorithm where the pixels corresponding to the same wavelength in each unit are identified through spatial- and frequency-domain interferometric signatures of a mirror sample. The utility of dual spectrometer-based SD-OCT imaging is demonstrated through in vivo retinal imaging at two different operation modes with high-speed and dual balanced acquisitions, respectively, in which the spectral alignment is critical to achieve improved retinal image data without any artifacts caused by misalignment of the spectrometers.
Original language | English (US) |
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Pages (from-to) | 1685-1701 |
Number of pages | 17 |
Journal | Biomedical Optics Express |
Volume | 13 |
Issue number | 3 |
DOIs | |
State | Published - Mar 2022 |
ASJC Scopus subject areas
- Biotechnology
- Atomic and Molecular Physics, and Optics