Ocular Surface Erosion after Suspected Exposure to Evaporated COVID-19 Vaccine

Somporn Chantra, Pareena Chaitanuwong, Kasem Seresirikachorm, Mitchell Brinks, Onsiri Serirat, Winston Chamberlain, Paisan Ruamviboonsuk

Research output: Contribution to journalArticlepeer-review


The purpose is to report ocular surface erosion of health personnel who were exposed to evaporated CoronaVac during a vaccination campaign. A campaign for CoronaVac vaccination was conducted in a closed space of 11.04 × 5.96 m, partially divided into 6 rooms with interconnected area among the rooms. A total of 20 health personnel worked in the vaccination rooms. On the third day of campaign, a vial, containing a single dose of 0.5 mL, of the vaccine was dropped accidentally onto the floor and broken by an administering nurse. A total of 15 personnel had symptoms and signs of ocular surface erosion at the average time from the accident to the onset of 10.2 ± 7.1 h; 4 personnel also had skin rash. These personnel included all 13 persons who already worked in the rooms when the accident occurred and continued for additional 4-6 h and 2 personnel who presented in the rooms 1-2 h after the accident and stayed for 2-3 h. Proximity and timing suggest CoronaVac correlation with the ocular and skin reactions. Cautions should be taken to avoid broken vials, spills, and aerosolization of CoronaVac during the vaccination.

Original languageEnglish (US)
Pages (from-to)944-951
Number of pages8
JournalCase Reports in Ophthalmology
Issue number3
StatePublished - Dec 2 2021


  • COVID-19 vaccine
  • Case report
  • Health worker
  • Ocular surface erosion
  • Skin rash

ASJC Scopus subject areas

  • Ophthalmology


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