“On‐Off”–induced lethal hyperthermia

Ronald F. Pfeiffer, Eugene L. Sucha

Research output: Contribution to journalArticlepeer-review

53 Scopus citations


Neuroleptic malignant syndrome (NMS) is being increasingly recognized as a potential complication of neuroleptic therapy. Similar hyperthermic episodes have also been described in other settings of adrupt cessation of dopaminergic stimulation such as levodopa withdrawal. We report a fatal NMS‐like episode occurring as a complication of an “off” period in a patient with Parkinson's disease.

Original languageEnglish (US)
Pages (from-to)338-341
Number of pages4
JournalMovement Disorders
Issue number4
StatePublished - 1989
Externally publishedYes


  • Malignant hyperthermia
  • Neuroleptic malignant syndrome

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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