TY - JOUR
T1 - Optical properties of intralipid
T2 - A phantom medium for light propagation studies
AU - Flock, Stephen T.
AU - Jacques, Steven L.
AU - Wilson, Brian C.
AU - Star, Willem M.
AU - van Gemert, Martin J.C.
PY - 1992
Y1 - 1992
N2 - Intralipid™ is an intravenous nutrient consisting of an emulsion of phospholipid micelles and water. Because Intralipid is turbid and has no strong absorption bands in the visible region of the electromagnetic spectrum, and is readily available and relatively inexpensive, it is often used as a tissue simulating phantom medium in light dosimetry experiments. In order to assist investigators requiring a controllable medium that over a finite range of wavelengths is optically equivalent to tissue, we have compiled previously published values of the optical interaction coefficients of Intralipid, most of which were measured at a wavelength of 633 nm. We have extended the measurements of the absorption and reduced scattering coefficients from 460 to 690 nm and the total attenuation coefficient from 500 to 890 nm. These measurements show that, for stock 10% Intralipid, the absorption coefficient varies from 0.015 to 0.001 cm−1 between 460 and 690 nm, the reduced scattering coefficient varies from 92 to 50 cm−1 between 460 and 690 nm, the total attenuation coefficient varies from 575 to 150 cm−1 between 500 and 890 nm, and the average cosine of scatter varies from 0.87 to 0.82 between 460 and 690 nm. With these data, we discuss the design of an optically tissue‐equivalent phantom consisting of Intralipid and black India ink. © 1992 Wiley‐Liss, Inc.
AB - Intralipid™ is an intravenous nutrient consisting of an emulsion of phospholipid micelles and water. Because Intralipid is turbid and has no strong absorption bands in the visible region of the electromagnetic spectrum, and is readily available and relatively inexpensive, it is often used as a tissue simulating phantom medium in light dosimetry experiments. In order to assist investigators requiring a controllable medium that over a finite range of wavelengths is optically equivalent to tissue, we have compiled previously published values of the optical interaction coefficients of Intralipid, most of which were measured at a wavelength of 633 nm. We have extended the measurements of the absorption and reduced scattering coefficients from 460 to 690 nm and the total attenuation coefficient from 500 to 890 nm. These measurements show that, for stock 10% Intralipid, the absorption coefficient varies from 0.015 to 0.001 cm−1 between 460 and 690 nm, the reduced scattering coefficient varies from 92 to 50 cm−1 between 460 and 690 nm, the total attenuation coefficient varies from 575 to 150 cm−1 between 500 and 890 nm, and the average cosine of scatter varies from 0.87 to 0.82 between 460 and 690 nm. With these data, we discuss the design of an optically tissue‐equivalent phantom consisting of Intralipid and black India ink. © 1992 Wiley‐Liss, Inc.
KW - intralipid
KW - light‐dosimetry
KW - optical‐interaction‐coefficients
KW - phantom
KW - radiative‐transfer
KW - similarity
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U2 - 10.1002/lsm.1900120510
DO - 10.1002/lsm.1900120510
M3 - Article
C2 - 1406004
AN - SCOPUS:0026630107
SN - 0196-8092
VL - 12
SP - 510
EP - 519
JO - Lasers in Surgery and Medicine
JF - Lasers in Surgery and Medicine
IS - 5
ER -