Oxygen reserve and autoregulation in the cochlea

M. Lawrence, A. L. Nuttall, P. A. Burgio

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


Endoiymphatic O2-concentration was measured in the guinea pig cochlea with a microelectrode inserted through the zona pectinata of the basilar membrane and the cells of Claudius, so as not to interfere with the blood supply to the organ of Corti. The O2-level and the amplitude of the cochlear potentials were followed during hypoxia produced by lowering the pO2 of the inspired air. Persistence of a normal endolymphatic O2-Ievel following the fall in arterial pO2 indicated an O2-reserve and an autoregulation of the cochlear circulation.

Original languageEnglish (US)
Pages (from-to)146-152
Number of pages7
JournalActa Oto-Laryngologica
Issue number1-6
StatePublished - 1977
Externally publishedYes

ASJC Scopus subject areas

  • Otorhinolaryngology


Dive into the research topics of 'Oxygen reserve and autoregulation in the cochlea'. Together they form a unique fingerprint.

Cite this