Palmoplantar keratoderma with progressive gingivitis and recurrent pyodermas

Tyler A. Moss, Anne P. Spillane, Sam F. Almquist, Patrick E. McCleskey, Oliver J. Wisco

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Papillon-Lefèvre syndrome (PLS) is a rare inherited palmoplantar keratoderma (PPK) that is associated with progressive gingivitis and recurrent pyodermas. We present a case exhibiting classic features of this autosomal-recessive condition and review the current understanding of its pathophysiology, diagnosis, and treatment. Additionally, a review of pertinent transgredient PPKs is undertaken, with key and distinguishing features of each syndrome highlighted.

Original languageEnglish (US)
Pages (from-to)193-198
Number of pages6
Issue number4
StatePublished - Apr 2014
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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