Parkinson's disease

Ali Samii; John G. Nutt; Bruce R. Ransom

doi:10.1016/S0140-6736(04)16305-8

Parkinson's disease

Ali Samii, John G. Nutt, Bruce R. Ransom

Neurology

Research output: Contribution to journal › Article › peer-review

1079 Scopus citations

Abstract

Parkinson's disease is the most common serious movement disorder in the world, affecting about 1% of adults older than 60 years. The disease is attributed to selective loss of neurons in the substantia nigra, and its cause is enigmatic in most individuals. Symptoms of Parkinson's disease respond in varying degrees to drugs, and surgery offers hope for patients no longer adequately controlled in this manner. The high prevalence of the disease, and important advances in its management, mean that generalists need to have a working knowledge of this disorder. This Seminar covers the basics, from terminology to aspects of diagnosis, treatment, and pathogenesis.

Original language	English (US)
Pages (from-to)	1783-1793
Number of pages	11
Journal	Lancet
Volume	363
Issue number	9423
DOIs	https://doi.org/10.1016/S0140-6736(04)16305-8
State	Published - May 29 2004

ASJC Scopus subject areas

General Medicine

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10.1016/S0140-6736(04)16305-8

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abstract = "Parkinson's disease is the most common serious movement disorder in the world, affecting about 1% of adults older than 60 years. The disease is attributed to selective loss of neurons in the substantia nigra, and its cause is enigmatic in most individuals. Symptoms of Parkinson's disease respond in varying degrees to drugs, and surgery offers hope for patients no longer adequately controlled in this manner. The high prevalence of the disease, and important advances in its management, mean that generalists need to have a working knowledge of this disorder. This Seminar covers the basics, from terminology to aspects of diagnosis, treatment, and pathogenesis.",

author = "Ali Samii and Nutt, {John G.} and Ransom, {Bruce R.}",

note = "Funding Information: We thank Kass Klemz for assistance with manuscript preparation. This work was made possible by funding from the National Institutes of Health (AS, JGN, BRR), the Department of Veterans Affairs through the Parkinson Disease Research Education and Clinical Center grant (AS, JGN), and the National Parkinson Foundation (JGN). The sponsor had no role in planning or writing of this Seminar.",

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AU - Samii, Ali

AU - Nutt, John G.

AU - Ransom, Bruce R.

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AB - Parkinson's disease is the most common serious movement disorder in the world, affecting about 1% of adults older than 60 years. The disease is attributed to selective loss of neurons in the substantia nigra, and its cause is enigmatic in most individuals. Symptoms of Parkinson's disease respond in varying degrees to drugs, and surgery offers hope for patients no longer adequately controlled in this manner. The high prevalence of the disease, and important advances in its management, mean that generalists need to have a working knowledge of this disorder. This Seminar covers the basics, from terminology to aspects of diagnosis, treatment, and pathogenesis.

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Parkinson's disease

Abstract

ASJC Scopus subject areas

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