Partial amino acid sequence of rat pre prolactin

R. A. Maurer, J. Gorski, D. J. McKean

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Rat pituitary mRNA was used to direct the cell-free synthesis of pre-prolactin labelled with [4,5-3H]leucine and either [35S]methionine or [35S]cystine. Sequence analysis of the labelled protein indicates that pre-prolactin has 29 amino acid residues joined to the N-terminus of the prolactin sequence. Leucine residues were found at positions 13, 14, 15, 16, 21 and 22, methionine residues at positions 1, 17 and 18, and a cysteine residue at position 24 of the precursor sequence, and this partial sequence shows considerable similarity with other precursors that have been sequenced.

Original languageEnglish (US)
Pages (from-to)189-192
Number of pages4
JournalBiochemical Journal
Issue number1
StatePublished - 1977
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology


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