Patients with disorders of thrombosis and hemostasis

Andrea Orfanakis, Thomas DeLoughery

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations


Surgery, by definition, is a challenge to the hemostatic system. In addition, a surgical procedure may provoke inappropriate venous or arterial thrombosis, such as is suggested historically by Virchow's Triad. For these reasons, proper functioning of the hematologic system is integral in a successful and safe perioperative period. Patients with a disorder of either coagulation or hemostasis, therefore, present an exciting challenge to the preoperative physician. Diagnosis of a hematologic disorder may be more or less occult. A proper bleeding and clotting history can serve to elucidate such a disorder and is therefore paramount to the preoperative workup. For those patients with a previously diagnosed disorder of the hematologic system, appropriate laboratory investigation and a concise therapeutic plan for the day of surgery can help to minimize risks in the perioperative period.

Original languageEnglish (US)
Pages (from-to)1161-1180
Number of pages20
JournalMedical Clinics of North America
Issue number6
StatePublished - Nov 2013


  • Coagulation
  • Hemostasis
  • Perioperative management
  • Thrombosis

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Patients with disorders of thrombosis and hemostasis'. Together they form a unique fingerprint.

Cite this