TY - JOUR
T1 - Patients with disorders of thrombosis and hemostasis
AU - Orfanakis, Andrea
AU - DeLoughery, Thomas
PY - 2013/11
Y1 - 2013/11
N2 - Surgery, by definition, is a challenge to the hemostatic system. In addition, a surgical procedure may provoke inappropriate venous or arterial thrombosis, such as is suggested historically by Virchow's Triad. For these reasons, proper functioning of the hematologic system is integral in a successful and safe perioperative period. Patients with a disorder of either coagulation or hemostasis, therefore, present an exciting challenge to the preoperative physician. Diagnosis of a hematologic disorder may be more or less occult. A proper bleeding and clotting history can serve to elucidate such a disorder and is therefore paramount to the preoperative workup. For those patients with a previously diagnosed disorder of the hematologic system, appropriate laboratory investigation and a concise therapeutic plan for the day of surgery can help to minimize risks in the perioperative period.
AB - Surgery, by definition, is a challenge to the hemostatic system. In addition, a surgical procedure may provoke inappropriate venous or arterial thrombosis, such as is suggested historically by Virchow's Triad. For these reasons, proper functioning of the hematologic system is integral in a successful and safe perioperative period. Patients with a disorder of either coagulation or hemostasis, therefore, present an exciting challenge to the preoperative physician. Diagnosis of a hematologic disorder may be more or less occult. A proper bleeding and clotting history can serve to elucidate such a disorder and is therefore paramount to the preoperative workup. For those patients with a previously diagnosed disorder of the hematologic system, appropriate laboratory investigation and a concise therapeutic plan for the day of surgery can help to minimize risks in the perioperative period.
KW - Coagulation
KW - Hemostasis
KW - Perioperative management
KW - Thrombosis
UR - http://www.scopus.com/inward/record.url?scp=84886768062&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84886768062&partnerID=8YFLogxK
U2 - 10.1016/j.mcna.2013.07.004
DO - 10.1016/j.mcna.2013.07.004
M3 - Review article
C2 - 24182725
AN - SCOPUS:84886768062
SN - 0025-7125
VL - 97
SP - 1161
EP - 1180
JO - Medical Clinics of North America
JF - Medical Clinics of North America
IS - 6
ER -