Patterns of photoprotection following CDKN2A/p16 genetic test reporting and counseling

Lisa G. Aspinwall, Samantha L. Leaf, Wendy Kohlmann, Erin R. Dola, Sancy A. Leachman

Research output: Contribution to journalArticlepeer-review

33 Scopus citations


Background: The impact of melanoma genetic testing and counseling on photoprotective behaviors is unknown. Objective: To determine if genetic testing and counseling alter compliance with photoprotection recommendations. Methods: Reported use of sunscreen, protective clothing, and sun avoidance by 59 members of CDKN2A/p16-mutation positive pedigrees was assessed as a function of mutation status and melanoma history, before, immediately after, and 1 month following test reporting. Results: Intentions to practice all photoprotective behaviors increased in all participant groups (P < .0001). At 1 month, 33% of participants reported the adoption of a new photoprotective behavior. Subpopulation analyses identified different patterns of change in photoprotection relative to baseline (P < .005), with no net decline in any group. Limitations: This initial study of CDKN2A/p16 families is small and awaits replication in a larger sample. Conclusion: Melanoma genetic testing and counseling enhanced intentions to implement photoprotective strategies and did not result in reduced compliance in the CDKN2A/p16-subpopulation.

Original languageEnglish (US)
Pages (from-to)745-757
Number of pages13
JournalJournal of the American Academy of Dermatology
Issue number5
StatePublished - May 2009
Externally publishedYes


  • CDKN2A
  • UV exposure
  • familial melanoma
  • genetic counseling
  • prevention
  • sunscreen use

ASJC Scopus subject areas

  • Dermatology


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