Pharmacoeconomics of Parenteral Nutrition with ω-3 Fatty Acids in Hospitalized Adults

Lorenzo Pradelli, Maurizio Muscaritoli, Stanislaw Klek, Robert G. Martindale

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations


The inclusion of ω-3 fatty acids as part of parenteral nutrition is associated with clinical benefits such as a reduced likelihood of infectious complications and shorter hospital and intensive care unit (ICU) stays. As healthcare resources are limited, pharmacoeconomic analyses have been performed, typically modeling studies, using cost and outcomes data to investigate the cost-effectiveness of parenteral nutrition regimens including ω-3 fatty acids from fish oil compared with standard parenteral nutrition without such ω-3 fatty acids. This review covers pharmacoeconomic studies encompassing Italian, French, German, and UK hospitals for ICU and non-ICU hospitalized patients, and for ICU patients in China. The results show that the use of parenteral nutrition including ω-3 fatty acids more than offsets any additional acquisition costs in all national scenarios investigated to date, indicating that parenteral nutrition including ω-3 fatty acids is a clinically and economically beneficial strategy compared with standard parenteral nutrition.

Original languageEnglish (US)
Pages (from-to)S68-S73
JournalJournal of Parenteral and Enteral Nutrition
Issue numberS1
StatePublished - Feb 1 2020


  • China
  • Europe
  • cost-effectiveness
  • fish oil
  • infections
  • intensive care
  • lipids
  • omega-3
  • parenteral nutrition
  • pharmacoeconomics

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics


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